It's been a while, but, as I recall, there were two clusters - Jenny and her lodgers, or Ashley and the dorm gang - with an early choice between the two limiting who you got close to, but also Jenny and Ashley eventually meeting and approving of each other, suggesting there might be some degree of crossover/merging in the future.
Checking the walkthrough quickly, there are tags for both AshHarem and JenHarem routes, so there were planned poly relationships with each of them, even if they never got further than, for example, Jade talking about threesomes...