this game prevents Hot-keys.
generally, after install BepInEx.GraphicsSettings & BepInEx.ConfigurationManager, press F1 bring to config window.
View attachment 4388125
but this game blocks.
so you can manually edit a BepInEx\config\keelhauled.graphicssettings.cfg file. options are commented in the cfg file. for example,
this explains feature & values. you can use one of "Disabled, Enabled, Half, Default" values.
in case of manual edit, you don't needed a BepInEx.ConfigurationManager.
edit .cfg file with a windows notepad.
about install BepInEx & plugins, check this
movie clip.